Number of pages: 100 | Report Format: PDF | Published date: March 03, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
According to the deep-dive market assessment study by Growth Plus Reports, the global creatinine testing market was valued at US$ 990.1 million in 2022 and is expected to register a revenue CAGR of 15.0% to reach US$ 4,005.5 million by 2031.
Creatinine Testing Market Fundamentals
A creatinine test determines how well the kidneys filter waste from the blood. Creatinine is a chemical substance produced by the energy-generating processes in muscles. Each kidney has millions of nephrons, which are small blood-filtering units. The nephrons regularly filter blood through glomeruli, small clusters of blood vessels. These structures release toxins, excess water, and other pollutants from the blood. Toxins are accumulated in the bladder and then eliminated by urination. Physicians use creatinine levels in the blood to assess kidney function. Elevated creatinine levels suggest that the kidney is damaged and not functioning properly. Creatinine blood tests are typically performed with a blood urea nitrogen test and a basic metabolic panel or comprehensive metabolic panel. These tests are performed during routine physical examinations to help with the identification of certain disorders and to check for any abnormalities in kidney function.
Creatinine is clinically significant due to its continual renal elimination. As creatinine is not expelled or reabsorbed by the tubules, determining creatinine clearance is a valuable parameter to measure the kidney’s glomerular filtration. The test methods for detecting creatinine in serum, urine, and muscle are unspecific color assays. Color reactions with 3,5-dinitrobenzoic acid, mercury thiocyanate potassium salts, and 1,4-naphthoquinone-2-sulphonate are among these. The most prevalent is the Jaffe reaction, in which creatinine and picric acid generate orange-red color in alkaline conditions. The specificity of this reaction can be enhanced by absorbing creatinine on Lloyd’s reagents—aluminum silicate and kaolin.
Creatinine testing is performed using a specific creatinine assay kit and can be conducted for many reasons, including hypertension, diabetes, and cancer. According to the International Society of Nephrology, there are around 13.3 million cases of acute kidney injury (AKI) worldwide yearly, with an annual incidence of 11.3 million in developing countries. The creatinine test kits market is driven by an increase in the prevalence of renal illnesses and other chronic conditions, technical improvements in biomedical research pertinent to kidney disorders, and increased research and development activities. Creatinine assay kits test creatinine in biological samples without prior preparation. Improvements in measuring creatinine levels have aided in the early diagnosis of renal disease. The increase in the demand for mycobacteria detection in urine and a rise in the geriatric population suffering from renal disease are two factors driving the creatinine testing market.
Creatinine Testing Market Dynamics
The growing prevalence of chronic kidney disease (CKD) and diabetes, a rising geriatric population, and increasing research and development initiatives are expected to boost the global creatinine testing market in the near future. Furthermore, the introduction of exogenous marker elements, growth in government funding, and increase in clinical laboratory activities are all driving the global creatinine testing market. Clinical chemistry laboratories all over the world perform serum creatinine assays. Favorable reimbursements and technologically advanced designs developed by market manufacturers, such as occlusive cuffs or pumps with implant connections, are also expected to drive the expansion of this market.
Kidney-related disorders have been on the rise in recent years, needing various renal therapy. Renal patients must regularly check their urinary creatinine and albumin levels and ratios. Several urine testing strategies and techniques are utilized to diagnose and treat renal disease. Biochemical urine analysis, which determines the concentration of chemical compounds in the urine, is also an option.
Government programs encouraging kidney health are also helping push the market forward, as are new monitoring techniques and technological breakthroughs in kidney function tests. One such potential technological innovation is rapid creatinine measurement devices at the point of care. This helps minimize the requirement for highly skilled analytical professionals to carry out sophisticated monitoring operations, ultimately fueling market development.
Some obstacles that may impede market expansion include frequently changing regulatory policies, restricted usage of creatinine assay kits in IVD, and the finding of novel renal dysfunction biomarkers.
Creatinine Testing Market Ecosystem
The global creatinine testing market is analyzed from four perspectives: product type, application, end-user, and region.
Creatinine Testing Market by Product Type
Based on product type, the global creatinine testing market has been segmented into consumables and instruments.
The consumables segment is likely to dominate the market during the forecast period due to the increase in the usage of creatinine testing consumables, such as urine test strips, measurement kits, dipsticks, analyzers, cartridges, and reagents.
Creatinine Testing Market by Application
Based on the application, the global creatinine testing market has been segmented into urinary tract obstruction, renal failure, kidney cancer, and glomerulonephritis.
The urinary tract obstruction and renal failure segment is likely to dominate the market. Early detection is essential since most cases of blockage can be resolved, and a delay in treatment can result in irreparable kidney damage. Physicians may suspect obstruction due to symptoms, such as renal colic, signs of bladder distention, or a decrease in urine volume. It is uncommon to feel a distended kidney in the flank, except in cases where the kidney is significantly enlarged in infants, toddlers, or thin adults. A dilated bladder can occasionally be felt in the lower abdomen, just above the pubic bone.
The increasing prevalence of kidney stones due to changing lifestyles propels the urinary tract obstruction segment forward. Rising cancer and infection rates in kidney transplant patients fuel the urinary tract obstruction segment forward. The growing prevalence of hydronephrosis will drive the demand for urinary tract obstruction testing and treatment throughout the forecast period. The growing number of urinary tract obstruction catheter and stent producers and distributors is improving the availability of goods in underserved areas and enhancing the urinary tract obstruction segment revenue growth.
Creatinine Testing Market by End User
Based on end-user, the global creatinine testing market has been segmented into hospitals & clinics, diagnostic centers, and research institutes.
The hospitals & clinics segment is likely to dominate the market during the forecast period. As disease prevalence is increasing, medical technology is improving, and investments in research and development are expanding. Increased investments in the pharmaceutical sector, drug discovery developments, and funding from the public and private sectors all contribute to market revenue growth. Furthermore, the availability of cutting-edge technologies in several established hospitals and developing countries, advancements in healthcare infrastructure and clinics, and an increase in the acceptance of rapid testing and point-of-care diagnostics are all driving market expansion.
The diagnostic center segment is expected to register the fastest revenue growth during the forecast period due to continuous demand for various treatments and devices. The growing necessity for early diagnosis and the increasing acceptance of precision medicine are driving market expansion.
Creatinine Testing Market by Region
Based on region, the global creatinine testing market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East and Africa.
North America is expected to lead the creatinine testing market during the forecast period. High healthcare expenditure, the rising prevalence of various renal ailments, the presence of key market players, and the usage of advanced technology in new product development are some factors driving the creatinine testing market to expand. The rising prevalence of renal disorders and their underlying causes are expected to drive market expansion in North America. For instance, according to Kidney Foundation research published in 2020, around 4 million people in Canada have renal disease, with 46% of new patients under 65. The region’s considerable burden of chronic diseases is likely to increase the demand avenues in the creatinine testing market. In addition, bioMérieux received FDA approval in July 2022 for the revolutionary VIDAS NEPHROCHECK test to detect renal stress in patients at risk of AKI. The launch of new products and the region’s expanding improvements in urine analysis are driving market expansion.
Asia Pacific is expected to be the fastest-growing region during the projection period. This increase can be attributed to a rise in the demand for early diagnosis, a large patient pool, and technological advancements in this region. Also, the rising government focus on reducing the cases of chronic renal disorders is likely to boost the creatinine testing market growth in this region. Increasing awareness of creatinine testing methods, an aging population suffering from chronic diseases, such as diabetes and renal difficulties, and greater R&D efforts in the healthcare industry are some of the other major factors driving the Asia Pacific market’s rapid revenue growth. According to the first Longitudinal Ageing Study in India (LASI), launched in January 2020 by the Union Ministry of Family and Health Affairs, two out of every three older individuals in India have a chronic health condition. Thus, the rising number of chronic diseases in the country is expected to fuel revenue growth in the regional market in the next few years.
Creatinine Testing Market Competitive Landscape
The top market players are focusing on strategies, such as mergers and acquisitions, joint ventures, new product launches, agreements, and collaborations, to maintain their market position and increase their product base.
The prominent market players in the global creatinine testing market include:
Creatinine Testing Market Strategic Developments
A creatinine test determines how well the kidneys filter the waste in the blood. Creatinine is a chemical substance produced by the energy-generating processes in muscles. Each kidney has millions of nephrons, which are small blood-filtering units.
The consumables product type segment accounts for the largest revenue share of the global market.
The creatinine testing market is expected to reach 4,005.5 million by 2031.
The creatinine testing market is expected to register a revenue CAGR of 15.0% during the forecast period.
Some prominent market players in the global creatinine testing market include Abbott Laboratories, Thermo Fisher Scientific, Inc., and Abcam Plc.
*Insights on financial performance are subject to the availability of information in the public domain