Number of pages: 100 | Report Format: PDF | Published date: March 14, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
According to the deep-dive market assessment study by Growth Plus Reports, the global single-use bioreactors market was valued at US$ 3.5 billion in 2022 and is expected to register a revenue CAGR of 20.89% to reach US$ 19.30 billion by 2031.
Single-use Bioreactors Market Fundamentals
Single-use bioreactors are a type of bioreactor that are designed for one-time usage and then disposed of after use. Single-use bioreactors are made from plastic materials and are used to cultivate cells and microorganisms in various applications, such as biopharmaceutical manufacturing, vaccine production, and academic research. They have several advantages over traditional stainless-steel bioreactors, including reduced capital costs, shorter setup times, and easier cleaning and sterilization. They also reduce the risk of contamination since there is no need for cleaning and sterilization between batches. Single-use bioreactors come in different sizes and configurations, including stirred-tank, wave-mixed, and rocking-motion designs. They can be used for batch and continuous processes, and their flexibility allows for rapid scale-up and scale-down. Single-use bioreactors have become increasingly popular in the biopharmaceutical industry, and their usage is expected to continue to grow in the future.
Single-use Bioreactors Market Dynamics
The single-use bioreactors have become increasingly popular in the biopharmaceutical industry, and their usage is expected to continue to grow in the future. The demand for biopharmaceuticals, such as monoclonal antibodies (MAbs), vaccines, and cell and gene therapies, has grown rapidly. Single-use bioreactors are a cost-effective and efficient way to produce these products, and biopharmaceutical manufacturers are increasingly using them to meet the growing demand. This increased demand is leading to revenue growth in the global single-use bioreactors market.
Single-use bioreactors offer several advantages over traditional stainless-steel bioreactors, including lower capital costs, reduced cleaning and validation requirements, and greater flexibility in scaling up or down. These advantages make them particularly attractive to small and mid-sized biopharmaceutical companies and contract manufacturing organizations (CMOs).
Regulatory bodies, such as the FDA and EMA, have supported using single-use bioreactors in the biopharmaceutical industry. This has helped to increase their adoption and has offered biopharmaceutical companies greater confidence in their use. Overall, the global single-use bioreactors market is expected to grow in the coming years, driven by the increasing demand for biopharmaceuticals, technological advancements, cost savings, and regulatory support.
However, single-use bioreactors generally have a smaller working volume than traditional bioreactors. This may not be suitable for large-scale production. Single-use bioreactors are designed for one-time usage and cannot be reused. This can concern companies looking to reduce costs and improve sustainability. Single-use bioreactors may not be suitable for certain applications, such as high-pressure fermentation, large-scale production, or long-term culture, leading to limited revenue growth in the global market.
Single-use Bioreactors Market Ecosystem
The global single-use bioreactors market has been analyzed from four perspectives: product type, cell type, molecule type, end user, and region.
Single-Use Bioreactors Market by Product Type
Based on product type, the global single-use bioreactors market has been segmented into single-use media bags, single-use bioreactor systems, single-use filtration assemblies, and other products. The single-use media bags are further sub-segmented into 2D Bags, 3D Bags, and Others. The single-use bioreactor systems are further sub-segmented into up to 10L, 11-100L, 101-500L, 501-1500L, and above 1500L.
The single-use bioreactor systems segment accounts for the largest revenue share in the global market. They are commonly employed in biopharmaceutical manufacturing procedures that call for high product yield. Single-use bioreactors’ adaptability, affordability, and high capacity for mass manufacturing would raise demand for the goods and spur rapid market expansion. The segment is expected to grow due to the rising need for quick development and increased production of new bio-therapeutics, such as vaccines, antibodies, enzymes, and hormones, as well as an increase in the product quantities generated in these bioreactors.
Single-Use Bioreactors Market by Cell Type
Based on cell type, the global single-use bioreactors market has been segmented into bacterial cells, mammalian cells, yeast, and other cell types.
The mammalian cells segment accounted for the largest global single-use bioreactors market revenue share due to the substantial usage of these cells in developing biopharmaceutical therapeutics and the widespread commercial success of recombinant proteins produced from mammalian cells. Mammalian cell cultures are used to create 85.0% of the biopharmaceutical candidates under clinical development, according to BioProcess International.
The yeast segment is projected to grow at a high revenue CAGR during the forecast period. In addition to providing specific advantages in producing therapeutic recombinants, yeasts are dependable eukaryotic hosts for synthesizing heterologous proteins. The usage of yeast cells in clinical or therapeutic settings is receiving increasing attention from scientists and research organizations, which is projected to be responsible for the growth of this segment throughout the forecast period.
Single-Use Bioreactors Market by Molecule Type
Based on molecule type, the global single-use bioreactors market has been segmented into monoclonal antibodies, stem cells, recombinant proteins, vaccines, and others.
The monoclonal antibodies segment accounts for the largest revenue share in the global single-use bioreactors market. MAbs originate from a biological source and can continue to manufacture antibodies over time, making them particularly advantageous for treating various illnesses, including autoimmune disorders, leukemia, and lymphoma. While using disposables (single-use bioreactors) eliminates the need for cleaning, sterilization, and cleaning validation stages, lowering cost and batch operation time. As a result, the usage of single-use bioreactors for creating and manufacturing MAbs is expanding along with the need for MAb manufacturing. Thus, it is projected to boost segment revenue growth during the forecast period.
Single-Use Bioreactors Market by End User
Based on end-user, the global single-use bioreactors market has been segmented into pharmaceutical & biopharmaceutical companies, CROs & CMOs, and academic & research institutes.
The pharmaceutical and biopharmaceutical companies segment accounts for the largest revenue share in the global single-use bioreactors market. Single-use bioreactors are becoming increasingly popular in the pharmaceutical and biopharmaceutical industries due to the rapid evolution of disposable technology, cost-effectiveness, and increasing government incentives for biopharmaceutical research. This trend is being embraced by pharmaceutical and biopharmaceutical organizations. Single-use bioreactors have become increasingly useful for various applications in the pharmaceutical and biopharmaceutical industries, including bioproduction, research, and process development. Hence, one of the key reasons fueling the growth of this market globally is the rising need for bioproduction and medical research. Another factor driving demand for single-use bioreactors among pharmaceutical and biopharmaceutical organizations is the growing availability of public and private funding in the healthcare industry.
The CROs & CMOs segment is projected to be the fastest-growing segment during the forecast period. The CROs & CMOs segment is projected to rise due to the rising outsourcing of research and development and production services by pharmaceutical and biopharmaceutical businesses. Several CROs are also heavily involved in extending their single-use bioreactor service offerings. This makes it possible for them to benefit from several factors, including time savings, total cost-effectiveness, and the ability to offer successful results to clients, all of which ultimately contribute to the revenue growth of this segment.
Single-Use Bioreactors Market by Region
Based on region, the global single-use bioreactors market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America accounted for the largest revenue share of the single-use bioreactors market. The demand for single-use bioreactors is projected to be driven by the well-established biopharmaceutical sector as well as the growing availability of innovative technologies. DNA sequencing is another crucial area that necessitates the study of molecular, cellular, and DNA architecture. Also, the innovative drug discovery carried out by the pharmaceutical and biopharmaceutical sectors is predicted to drive this market’s progress. The biopharmaceutical industry is developing rapidly to provide patients with immunizations. Furthermore, the demand for single-use bioreactors is expected to rise during the forecast period due to the region’s growing need to create biologics.
The single-use bioreactors market in Asia Pacific is expected to grow significantly in the coming years. The increasing demand for biopharmaceuticals and the advantages of single-use bioreactors, such as lower capital expenditure, reduced cleaning and validation costs, and faster turnaround times, drive the market’s revenue growth. China is expected to dominate the single-use bioreactors market in the region due to its large population and increase in the demand for biopharmaceuticals. Other key factors driving the revenue growth of the single-use bioreactors market in the Asia Pacific region include the rising adoption of single-use technologies by biopharmaceutical manufacturers, the growing number of CMOs in the region, and the availability of government funding for biopharmaceutical research and development.
Single-use Bioreactors Market Competitive Landscape
The prominent players operating in the global single-use bioreactors market are:
Single-use Bioreactors Market Strategic Developments
The global single-use bioreactors market is expected to grow at a revenue CAGR of 20.89% during the forecast period.
Thermo Fisher Scientific, Danaher Corporation, Merck KgaA, Sartorius Stedim Biotech, and Getinge AB are among the key players in the global single-use bioreactors market.
The single-use bioreactors systems segment accounts for the largest revenue share in the global single-use bioreactors market.
Asia Pacific is expected to observe the highest revenue growth in the global single-use bioreactors market during the forecast period.
The global single-use bioreactors market was valued at US$ 3.5 billion in 2022.
*Insights on financial performance are subject to the availability of information in the public domain