Number of pages: 100 | Report Format: PDF | Published date: March 14, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
Report Attribute |
Details |
Market size value in 2022 |
US$ 3.5 billion |
Revenue forecast in 2031 |
US$ 19.30 billion |
Growth Rate |
CAGR of 20.89% from 2023 to 2031 |
Base Year for Estimation |
2022 |
Forecast Period |
2023-2031 |
Historical Year |
2021 |
Segments Covered |
Product Type, Cell Type, Molecule Type, End User, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global single-use bioreactors market was valued at US$ 3.5 billion in 2022 and is expected to register a revenue CAGR of 20.89% to reach US$ 19.30 billion by 2031.
Market Fundamentals
Single-use bioreactors are a type of bioreactor that are designed for one-time use and then disposed of after use. Single-use bioreactors are made from plastic materials and are used to cultivate cells and microorganisms in various applications, such as biopharmaceutical manufacturing, vaccine production, and academic research. Single-use bioreactors have several advantages over traditional stainless-steel bioreactors, including reduced capital costs, shorter setup times, and easier cleaning and sterilization. They also reduce the risk of contamination, since there is no need for cleaning and sterilization between batches. Single-use bioreactors come in different sizes and configurations, including stirred-tank, wave-mixed, and rocking-motion designs. They can be used for batch and continuous processes, and their flexibility allows for rapid scale-up and scale-down. Single-use bioreactors have become increasingly popular in the biopharmaceutical industry, and their use is expected to continue to grow in the future.
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Market Dynamics
The single-use bioreactors have become increasingly popular in the biopharmaceutical industry, and their use is expected to continue to grow in the future. The demand for biopharmaceuticals, such as monoclonal antibodies, vaccines, and cell and gene therapies, has grown rapidly. Single-use bioreactors are a cost-effective and efficient way to produce these products, and biopharmaceutical manufacturers are increasingly using them to meet the growing demand. This increased demand leads to growth in the global single-use bioreactors market.
Single-use bioreactors offer several advantages over traditional stainless-steel bioreactors, including lower capital costs, reduced cleaning and validation requirements, and greater flexibility in scaling up or down. These advantages make them particularly attractive to small and mid-sized biopharmaceutical companies and contract manufacturing organizations (CMOs).
Regulatory bodies such as the FDA and EMA have supported using single-use bioreactors in the biopharmaceutical industry. This has helped to increase their adoption and has given biopharmaceutical companies greater confidence in their use. Overall, the global single-use bioreactors market is expected to grow in the coming years, driven by increasing demand for biopharmaceuticals, technological advancements, cost savings, and regulatory support.
However, several factors may act as restraints for the single-use bioreactors market. Single-use bioreactors generally have a smaller working volume than traditional bioreactors. This may not be suitable for large-scale production. Single-use bioreactors are designed for one-time use and cannot be reused. This can concern companies looking to reduce costs and improve sustainability. Single-use bioreactors may not be suitable for certain applications such as high-pressure fermentation, large-scale production, or long-term culture.
The global single-use bioreactors market has been analyzed from four perspectives: product type, cell type, molecule type, end user, and region.
Single-Use Bioreactors Market by Product Type
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Based on product type, the global single-use bioreactors market has been segmented into single-use media bags, single-use bioreactor systems, single-use filtration assemblies, and other products. The single-use media bags are further segmented into 2D Bags, 3D Bags, and Others. The single-use bioreactor systems are further segmented into Up to 10L, 11-100L, 101-500L, 501-1500L, and above 1500L.
The single-use bioreactor systems account for the largest revenue share in the global market. They are frequently employed in biopharmaceutical manufacturing procedures that call for high product yield. Single-use bioreactors' adaptability, affordability, and high capacity for mass manufacturing would raise demand for the goods and spur rapid market expansion. The segment is expected to grow due to the rising need for quick development and increased production of new bio-therapeutics such as vaccines, antibodies, enzymes, and hormones, as well as an increase in the product quantities generated in these bioreactors.
Single-Use Bioreactors Market by Cell Type
The global single-use bioreactors market has been segmented based on cell type into bacterial cells, mammalian cells, yeast, and other cell types.
The mammalian cells segment accounted for the largest global single-use bioreactors market share. This is due to the substantial use of these cells in developing biopharmaceutical therapeutics and the widespread commercial success of recombinant proteins produced from mammalian cells. Mammalian cell cultures are used to create 85.0% of the biopharmaceutical candidates under clinical development, according to BioProcess International.
The yeast segment is projected to grow at a high revenue CAGR in the forecast period. In addition to providing specific advantages in producing therapeutic recombinants, yeasts are dependable eukaryotic hosts for synthesizing heterologous proteins. The usage of yeast cells in clinical or therapeutic settings is receiving increasing attention from scientists and research organizations, which will be responsible for the growth of this segment throughout the forecast period.
Single-Use Bioreactors Market by Molecule Type
The global single-use bioreactors market has been segmented based on molecule type into monoclonal antibodies, stem cells, recombinant proteins, vaccines, and others.
The monoclonal antibodies segment accounts for the largest revenue share in the global single-use bioreactors market. The fact that monoclonal antibodies (MAbs) originate from a biological source and can continue to manufacture antibodies over time makes them particularly advantageous for treating various illnesses, including autoimmune disorders, leukemia, and lymphoma. While using disposables (single-use bioreactors) eliminates the need for cleaning, sterilization, and cleaning validation stages, lowering cost and batch operation time. As a result, the usage of single-use bioreactors (SUBs) for creating and manufacturing monoclonal antibodies is expanding along with the need for MAb manufacturing. Thus, it is projected to boost segment growth even during the forecast period.
Single-Use Bioreactors Market by End User
Based on end user, the global single-use bioreactors market has been segmented into pharmaceutical & biopharmaceutical companies, CROs & CMOs, and academic & research institutes.
The pharmaceutical and biopharmaceutical companies segment accounted for the largest revenue share in the global single-use bioreactors market. Due to the fast development of disposable technology in the pharmaceutical and biopharmaceutical industries, cost-effectiveness, and growing government incentives for biopharmaceutical research, pharmaceutical, and biopharmaceutical organizations adopt single-use bioreactors. Single-use bioreactors have become increasingly useful for various applications in the pharmaceutical and biopharmaceutical industries, including bioproduction, research, and process development. Hence, one of the key reasons fueling the growth of this market globally is the rising need for bioproduction and medical research. Another factor driving demand for single-use bioreactors among pharmaceutical and biopharmaceutical organizations is the growing availability of public and private funding in the healthcare industry.
The CROs & CMOs segment is projected to be the fastest-growing segment during the forecast period. It is projected that the CROs & CMOs segment would rise because of the rising outsourcing of research and development and production services by pharmaceutical and biopharmaceutical businesses. Several CROs are also heavily involved in extending their single-use bioreactor service offerings. This makes it possible for them to benefit from several factors, including time savings, total cost-effectiveness, and the ability to give successful results to clients, all of which ultimately contribute to the growth of this segment.
Single-Use Bioreactors Market by Region
The global single-use bioreactors market has been segmented based on region into North America, Europe, Asia Pacific, Latin America, and The Middle East & Africa.
North America accounted for the largest global single-use bioreactors market revenue share. The demand for single-use bioreactors is projected to be driven by the well-established biopharmaceutical sector as well as the growing availability of innovative technologies. Another crucial area that necessitates the study of molecular, cellular, and DNA architecture is DNA sequencing. Also, the innovative drug discovery carried out by the pharmaceutical and biopharmaceutical sectors is predicted to drive this market's progress. The biopharmaceutical industry is moving extraordinarily quickly to provide patients with immunizations. Furthermore, during the course of the projection period, there is likely to be an increase in demand for the use of single-use bioreactors due to the nation's growing need for the creation of biologics.
The single-use bioreactors market in the Asia Pacific region is expected to grow significantly in the coming years. The increasing demand for biopharmaceuticals, coupled with the advantages offered by single-use bioreactors such as lower capital expenditure, reduced cleaning and validation costs, and faster turnaround times, is driving the market’s growth. China is expected to dominate the single-use bioreactors market in the region due to its large population and increasing demand for biopharmaceuticals. Other key factors driving the growth of the single-use bioreactors market in the Asia Pacific region include the increasing adoption of single-use technologies by biopharmaceutical manufacturers, the growing number of contract manufacturing organizations (CMOs) in the region, and the availability of government funding for biopharmaceutical research and development.
Competitive Landscape
Some of the prominent players operating in the global single-use bioreactors market are: -
Strategic Developments
The global single-use bioreactors market is expected to grow at a revenue CAGR of 20.89% in the forecast period.
Thermo Fisher Scientific, Danaher Corporation, Merck KgaA, Sartorius Stedim Biotech, and Getinge AB are a few key players in the global single-use bioreactors market.
The single-use bioreactors systems segment has the largest revenue share in the global single-use bioreactors market.
Asia Pacific region is expected to observe the highest global single-use bioreactors market growth in the forecast period.
The global single-use bioreactors market was valued at US$ 3.5 billion in 2022.
*Insights on financial performance are subject to the availability of information in the public domain