Nucleic Acid Decontamination Reagents Market
Number of pages: 100 | Report Format: PDF | Published date: March 23, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
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Report Attribute |
Details |
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Market Size Value in 2022 |
US$ 1.75 billion |
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Revenue forecast in 2031 |
US$ 3.61 billion |
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CAGR |
8.4% |
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Base Year for Estimation |
2021 |
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Forecast Period |
2023-2031 |
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Historical Year |
2022 |
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Segments Covered |
Type, End User, and Region |
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Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global nucleic acid decontamination reagents market was valued at US$ 1.75 billion in 2022 and is expected to register a revenue CAGR of 8.4% to reach US$ 3.61 billion by 2031.
Nucleic Acid Decontamination Reagents Market Fundamentals
Nucleic acid decontamination refers to removing or destroying nucleic acids that may be present on surfaces, equipment, or other materials in a laboratory or clinical setting. Nucleic acid decontamination is important to prevent cross-contamination and ensure accurate experimental results. For instance, short tandem repeat (STR) deoxyribonucleic acid (DNA) typing can be misinterpreted due to DNA contamination. In forensic DNA laboratories where the probative value of the evidence may be impacted, proper disinfection is very important. Several methods can be used for nucleic acid decontamination. UV irradiation involves exposing the material or surface to UV light, damaging the nucleic acids, and preventing replicating. Chemical disinfection, such as bleach, ethanol, or hydrogen peroxide, can disinfect surfaces and equipment. Enzymes, such as DNase and RNase, can digest nucleic acids on surfaces or in solutions. High temperatures can denature nucleic acids and make them non-functional. Autoclaving or dry heat sterilization are common methods for heat-based nucleic acid decontamination.
Choosing a decontamination method appropriate for the specific situation and material being decontaminated is important. Following proper safety protocols and guidelines when handling potentially contaminated materials is essential.
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Nucleic Acid Decontamination Reagents Market Dynamics
The need for nucleic acid decontamination has also increased with the growing demand for research activities in the life sciences and healthcare sectors. Researchers require pure and uncontaminated samples for accurate analysis and diagnosis. This factor drives the revenue growth of the global nucleic acid decontamination market. The healthcare and biotechnology industries are subject to strict regulations that require them to adhere to specific product safety and quality standards. This has led to the development of more effective decontamination methods and products. Healthcare professionals, researchers, and regulatory bodies have increasingly recognized nucleic acid decontamination. This has led to an increase in demand for effective and efficient decontamination products. Technological advancements have resulted in more efficient and effective nucleic acid decontamination methods and products. This has made the process faster, more reliable, and easier to perform. The need for nucleic acid decontamination has also increased with the increasing prevalence of infectious diseases. Decontamination helps prevent the spread of infectious diseases by removing or destroying the infectious agents from surfaces, instruments, and other materials. Thus, the above-mentioned factors are responsible for the revenue growth of the global nucleic acid decontamination reagents market.
Nucleic Acid Decontamination Reagents Market Ecosystem
The global nucleic acid decontamination reagents market has been analyzed from three perspectives: type, end user, and region.
Nucleic Acid Decontamination Reagents Market by Type
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Based on type, the global nucleic acid decontamination reagents market has been segmented into sodium hypochlorite-based, phosphoric acid-based, sodium hydroxide-based, non-enzymatic reagent, and others.
The sodium hypochlorite-based reagents segment accounts for the largest global nucleic acid decontamination reagents market revenue share. In molecular biology laboratories, sodium hypochlorite is commonly used as a reagent for nucleic acid decontamination. It is a strong oxidizing agent that can effectively degrade DNA and RNA molecules. Despite quick reaction times, all evaluated sodium hypochlorite-based reagents demonstrated substantial nucleic acid decontamination efficacy. Many key players, such as Thermo Fisher and Merck, manufacture these reagents.
The other segments, such as phosphoric acid-based and sodium hydroxide-based reagents, have shown little efficacy in reducing nucleic acid from a given surface compared to sodium hypochlorite-based reagents. These are sold under DNA-ExitusPlus, DNA Away, etc., and are commercially available.
Though other segments, such as UV radiation, have proved to be effective in the decontamination of nucleic acids, thus the prospect for revenue growth in this segment during the forecast period. For instance, before PCR setup, reagents, and equipment can be cleaned of nucleic acids using BioSan's UVT-S-AR UV workstation.
Nucleic Acid Decontamination Reagents Market by End User
Based on end user, the global nucleic acid decontamination reagents market has been segmented into hospitals, diagnostic laboratories, academic & research institutes, biopharmaceutical companies, and others.
The hospitals and diagnostic laboratories segment has the largest revenue share in the global nucleic acid decontamination reagents market. Nucleic acid decontamination is essential in diagnostic laboratories to prevent cross-contamination of samples and ensure accurate test results. Nucleic acid decontamination is a process that aims to remove or inactivate nucleic acids from surfaces, instruments, or samples to prevent contamination and ensure accurate test results in diagnostic laboratories. Nucleic acid decontamination is essential in preventing the contamination of samples, reagents, and equipment with foreign nucleic acids, which can interfere with the accuracy of experiments. Proper decontamination techniques should be employed before and after working with any nucleic acids. The increasing prevalence of various chronic diseases requires adequate diagnosis. This, in turn, requires pure and clean instruments and equipment. Thus, nucleic acid decontamination reagents can help decontaminate laboratory equipment, such as pipettes, centrifuges, and PCR machines.
The academic & research institutes and biopharmaceutical companies segments account for a small revenue share in the global nucleic acid decontamination reagents market. Nucleic acid decontamination is essential in academic institutes and pharma companies to maintain a clean and sterile laboratory environment and prevent the spread of infectious agents or genetically modified organisms. In academic institutes, nucleic acid decontamination is particularly important in research involving genetic engineering, PCR, cloning, and other molecular biology techniques that rely on amplifying and detecting nucleic acids. Cross-contamination of nucleic acids can lead to false-positive or false-negative results, compromising the integrity of research findings. Therefore, academic institutes must establish standard operating procedures for nucleic acid decontamination, including disinfectants, UV radiation, and physical barriers (for instance, laminar flow hoods) to prevent contamination.
In pharma companies, nucleic acid decontamination is critical in drug development and manufacturing processes that involve genetically engineered microorganisms or animal cells. The contamination of these cultures with foreign nucleic acids can affect the final product's safety, efficacy, and purity, potentially leading to adverse patient events. Therefore, pharma companies must follow strict guidelines for nucleic acid decontamination, such as using validated cleaning agents, sterilizing equipment and surfaces, and implementing microbial monitoring programs to detect any potential sources of contamination. As more and more research and drug development activities are increasing, there is an indirect increase in demand for nucleic acid decontamination reagents.
Nucleic Acid Decontamination Reagents Market by Region
Based on region, the global nucleic acid decontamination reagents market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
North America accounts for the largest global nucleic acid decontamination reagents market revenue share. Nucleic acid decontamination products are used to remove or inactivate nucleic acids from surfaces, equipment, and reagents to prevent cross-contamination and maintain the integrity of samples. Several companies, including Thermo Fisher Scientific, Promega Corporation, and Bio-Rad Laboratories, offer nucleic acid decontamination products in the North America market. These companies provide products, including nucleic acid removal kits, DNA-free reagents, and UV irradiation systems.
The nucleic acid decontamination reagents market in Asia will experience significant revenue CAGR in the coming years. The market is driven by increasing research activities in genomics, proteomics, and biotechnology, along with rising investments in life science research and development by governments and private organizations. Furthermore, the increasing demand for nucleic acid decontamination products, particularly in countries, such as China, Japan, South Korea, and India, is expected to propel the market revenue growth. Additionally, the growing prevalence of infectious diseases in the region is likely to contribute to market revenue growth, as nucleic acid decontamination products play a vital role in preventing the spread of diseases.
The increasing demand for molecular biology techniques in research, diagnostics, and therapeutics drives the market for nucleic acid decontamination reagents. This demand is expected to continue to grow in Latin America, as the region has a large population and an increasing number of research and clinical laboratories.
Nucleic Acid Decontamination Reagents Market Competitive Landscape
The prominent players operating in the global nucleic acid decontamination reagents market are:
Nucleic Acid Decontamination Reagents Market Strategic Developments
The global nucleic acid decontamination reagents market is expected to grow at a revenue CAGR of 8.4% during the forecast period.
Thermo Fisher Scientific Inc., Novolab, ITW Reagents, Minerva Biolabs, and Nanjing Vazyme Biotech Co. are among the key players in the global nucleic acid decontamination reagents market.
The sodium hypochlorite-based reagents segment accounts for the largest revenue share in the global nucleic acid decontamination reagents market.
Asia Pacific is expected to register the highest global nucleic acid decontamination reagents market revenue growth during the forecast period.
The global nucleic acid decontamination reagents market was valued at US$ 3.61 billion in 2022.
*Insights on financial performance are subject to the availability of information in the public domain