Number of pages: 100 | Report Format: PDF | Published date: March 20, 2023
Historical Years – 2021 | Base Year – 2022 | Forecasted Years – 2023-2031
Report Attribute |
Details |
Market Size Value in 2022 |
US$ 8.5 billion |
Revenue Forecast in 2031 |
US$ 19.71 billion |
CAGR |
9.8% |
Base Year for Estimation |
2022 |
Forecast Period |
2023-2031 |
Historical Year |
2021 |
Segments Covered |
Model Type, Application, End-user, and Region |
Regional Scope |
North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa |
According to the deep-dive market assessment study by Growth Plus Reports, the global humanized mice model market was valued at US$ 8.5 billion in 2022 and is expected to register a revenue CAGR of 9.8% to reach US$ 19.71 billion by 2031.
Humanized Mice Model Market Fundamentals
Humanized mice are genetically engineered laboratory animals possessing functional human genes, cells, or tissues. This type of mouse model is used in biomedical research to study human diseases and test potential therapies. Creating a humanized mouse involves transplanting human cells, tissues, or stem cells into immunodeficient mice lacking a functional immune system. This allows the human cells to grow and function within the mouse, creating a hybrid animal with human and mouse characteristics. Humanized mice have been used to study various diseases, including cancer, HIV/AIDS, autoimmune disorders, and infectious diseases, such as Zika and COVID-19. These models can provide valuable insights into disease mechanisms and the effectiveness of potential treatments. Humanized mice represent an important tool for biomedical research, offering a unique opportunity to bridge the gap between in vitro studies and human clinical trials. However, humanized mice have limitations like any animal model, and their results must be carefully interpreted and validated.
[67967]
Humanized Mice Model Market Dynamics
The global humanized mice model market has been experiencing steady growth in recent years. It is expected to continue to grow in the coming years. Humanized mice models are used in various fields, including immunology, infectious diseases, oncology, and regenerative medicine. One of the main drivers of the humanized mice model market revenue growth is the increasing demand for personalized medicine. Humanized mice models are useful in developing and testing customized therapies and treatments for specific diseases and conditions.
Another factor driving the growth of the global humanized mice model market is the increasing investment in research and development in the life sciences industry. With the growing understanding of the importance of personalized medicine and the rising need for targeted therapies, there has been a significant increase in research funding in life sciences. The growing prevalence of chronic and infectious diseases also drives the demand for humanized mice models for drug discovery and development. Humanized mice models are crucial in the preclinical testing of new drugs and therapies for these diseases.
However, the global market for humanized mouse models is being constrained by stringent regulations and legislations developed for the ethical usage of animals and expensive methods for maintaining animal housing. The market is projected to grow due to rising monoclonal antibody production and healthcare system improvements in developing countries.
Humanized Mice Model Market Ecosystem
The global humanized mice model market has been analyzed from four perspectives: model type, application, end-user, and region.
Humanized Mice Model Market by Model Type
[8956]
Based on the type, the global humanized mice model market has been segmented into cell-based humanized mice model and genetic humanized mice model.
The genetic humanized mouse model segment accounted for the largest revenue share in the global humanized mice model market. The significant market share of this segment can be attributable to the extensive usage of genetically humanized mice models in compound analysis, biological efficacy and safety testing, medication metabolism and disposition studies, and immune system development and function research. An essential tool in biomedical research is genetically humanized mouse models. They enable the study of human diseases in a regulated laboratory setting and the testing of putative treatments before they are applied to humans. They also allow research on the human immune system to be conducted in more realistic conditions, which can aid in creating new vaccines and treatments.
Humanized Mice Model Market by Application
Based on the application, the global humanized mice model market has been segmented into oncology, GvHD, neuroscience, toxicology, regenerative medicine, immunology & infectious diseases, and others.
The oncology segment is projected to observe a high revenue CAGR in the global humanized mice model market. This is driven by the rising incidence of cancer, expanding cancer research and development initiatives, and rising clinical demand that must be satisfied. Compared to cultured cancer cells, humanized mice models are considered more realistic study subjects for tumor biology. This is also predicted to considerably contribute to the market’s revenue growth throughout the forecast period.
Humanized Mice Model Market by End-user
Based on the end-user, the global humanized mice model market has been segmented into pharmaceutical and biotechnology companies, academic & research institutes, and contract research organizations (CROs).
The pharmaceutical and biotechnology companies segment accounts for the largest revenue share in the global humanized mice model market. The segment is anticipated to grow throughout the projected period as more infectious disease vaccines are produced using the rat and mouse model. Mice are frequently employed as model organisms to test potential vaccines because they have a well-defined genome, an immune system that is well-characterized, and the ability to reproduce quickly.
The contract research organizations segment is estimated to be the fastest growing, with a high revenue CAGR during the forecast period. The segment will grow due to an increase in the number of pharmaceutical corporations outsourcing their preclinical investigations to contract research organizations. Researchers and academicians are focusing on developing novel medicines and vaccines using humanized mouse models, as the information gathered from these models is useful in predicting the clinical outcome of certain pharmaceuticals currently under development. The pharmaceutical sector, CROs, academic institutions, and research centers are expected to seek these models to help the market.
Humanized Mice Model Market by Region
Based on region, the global humanized mice model market has been segmented into North America, Europe, Asia Pacific, Latin America, and the Middle East & Africa.
The humanized mice model market in North America is expected to grow in the coming years due to the increasing demand for personalized medicine, drug discovery and development, and immunology research. North America is a leading regional market for humanized mice models as the region houses several top pharmaceutical and biotechnology companies, world-renowned research institutions, and government support for biomedical research. The market is also driven by advancements in genetic engineering and the development of innovative technologies to create humanized mouse models. Moreover, rising expenditures on R&D by biotech and pharmaceutical firms are anticipated to drive market expansion. Rat and mouse models comprise 99.3% of the mammals employed in 16 significant American universities, according to a research paper published in January 2021. As a result, the region’s strong adoption of these models fuels revenue growth. Overall, North America’s humanized mice model market is expected to continue its growth trajectory due to the increasing demand for humanized models in drug discovery and development, cancer research, and immunology research.
Asia Pacific is expected to register robust revenue CAGR during the forecast period owing to the rapid growth of the biomedical sector, advancement in translational research, and increasing demand for precision medicine in India, China, Japan, and other Asia Pacific countries. China is expected to account for the largest revenue share in the region, owing to increasing animal research, mandatory animal testing for pharmaceutical drugs and cosmetics, the growing biomedical sector, and a rapid rise in strategic alliances between research institutes in China and international institutes and companies. In addition, the availability of a massive target patient pool, low cost of clinical trials, and favorable domestic regulatory scenario are also expected to drive revenue growth of the market in the region.
Humanized Mice Model Market Competitive Landscape
The prominent players operating in the global humanized mice model market are:
The global market for humanized mouse models has a fragmented competitive environment with many regional and international companies. To diversify their product offerings and establish a solid foothold in the global market, key companies are concentrating on R&D activities, technological innovation, and strategic alliances, such as mergers and acquisitions, collaborations, partnerships, and joint ventures.
Humanized Mice Model Market Strategic Developments
The global humanized mice model market is expected to register growth at a revenue CAGR of 9.8% during the forecast period.
Genoway S.A., Crown Bioscience Inc., HuMurine Technologies, Yecuris Corporation, and Taconic Biosciences, Inc. are a few key players in the global humanized mice model market.
The genetic humanized mice model segment accounts for the largest revenue share in the global humanized mice model market.
The increasing research activities involving humanized mice models, expanding biopharmaceutical sector, growing drug research and development activities, and rising demand for personalized medicine are expected to drive the global humanized mice model market revenue growth.
The global humanized mice model market was valued at US$ 8.5 billion in 2022.
*Insights on financial performance are subject to the availability of information in the public domain