Report Overview

Report Overview

The global cartilage repair market was valued at US$ 850.4 million in 2021, expected to witness a CAGR of 14.85% during the forecast period from 2022 to 2030.

Market Fundamentals

Cartilage is a thick, flexible connective tissue that decreases joint friction, binds bones together, and aids in weight support. It serves as a shock absorber and minimizes friction. If injured cartilage cannot heal on its own or with the help of physical therapy and medicine, an interventional approach for cartilage repair is used. Cartilage restoration treatment aims to restore the cartilage surface of an articular joint. 

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Market Dynamic

Growing healthcare expenditure, combined with technological advancements in cartilage repair, is likely to offer opportunities for manufacturers worldwide to introduce innovative products in the market. Furthermore, the rising prevalence of articular cartilage damage and osteoarthritis supports the market expansion. Growing demand and interest in regenerative medicine for cartilage restoration is another factor influencing the global market for cartilage repair. However, impeding factors for the development of the worldwide market are high costs and lack of insurance coverage in some regions.

Market Ecosystem

The global cartilage repair market has been analyzed from four perspectives: modality, treatment type, application, and region. 

Cartilage Repair Market by Modality  

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Based on modality, the global cartilage repair market is segmented into cell-based and non-cell-based treatments. The cell-based modality is further grouped into growth factor technology and chondrocyte transplantation. The non-cell-based treatments include tissue scaffolds and cell-free composites. Cell-based regenerative therapies for cartilage regeneration have become a standard practice for cartilage repair. For the treatment of significant cartilage abnormalities, matrix-assisted autologous chondrocyte transplantation (MACT) has demonstrated satisfactory long-term results regarding radiological, histological, and clinical outcomes. In non-cell-based treatment, tissue scaffold-based cell-free treatment is extensively used. 

Cartilage Repair Market by Treatment Type

The global cartilage repair market is segmented into palliative and intrinsic treatments based on treatment types. 

The intrinsic treatment segment dominated the global cartilage repair market. Intrinsic cartilage repair therapy provides long term improvement in pain management. Additionally, ease of availability, multilineage potential, and proliferative ability of intrinsic segment make it an excellent choice for cartilage repair. 

The palliative treatments are further segmented into debridement & lavage, and viscosupplementation. Among these, treatment with viscosupplementation is expected to dominate the market. The procedure involves the usage of hyaluronic acid, which reduces pain and swelling. Furthermore, viscosupplementation can also be used in outpatient clinics. 

Cartilage Repair Market by Application  

Based on application, the global cartilage repair market is grouped into fibrocartilage and hyaline cartilage. 

Hyaline cartilage segment accounts for the majority of market share. Hyaline cartilage contains a high concentration of collagen, a protein in connective tissues that helps hold the joints together. Different body parts are supported and made more flexible by this cartilage. Hyaline cartilage tissue is not capable of spontaneous regeneration. Therefore, using an engineered cartilage-like tissue or a cell-seeded scaffold material to cover a chondral defect is the most innovative method of repairing an articular cartilage lesion. 

Fibrocartilage acts as a joint stabilizer and shock absorber in knee joints that bear strain and stress by providing a cushion layer. Since the fibrocartilage in knee joints is significantly more sensitive to joint instability, it frequently serves as a warning sign of impending cartilage deterioration.

Cartilage Repair Market by Region 

Regionally, the global cartilage repair market has been segmented into North America, Europe, Asia Pacific, and the rest of the world. 

North America accounted for the most significant revenue share, owing to the extensive use of modern technologies in the healthcare sector, high obesity prevalence, increased investments in R&D of cutting-edge cartilage repair techniques, and increased healthcare spending. Additionally, the market in this region is experiencing revenue growth thanks to numerous significant competitors such as Stryker Corporation and Zimmer Biomet. 

The European market is characterized by increasing demand for cell-based repair methods; moreover, increasing healthcare expenditure in the region supports the expansion in Europe. 

Asia Pacific is predicted to register considerable revenue growth in the cartilage repair market during the forecast period due to the growing prevalences and rapidly developing healthcare infrastructure.  Furthermore, the expansion of the cartilage repair market in the region within the estimation period is rising due to the growing frequency of fractures brought on by osteoporosis.

Competitive Landscape

The prominent players operating in the global cartilage repair market are: 

• DePuy Synthes AG
• Smith & Nephew plc
• Zimmer Biomet Holdings, Inc. 
• Stryker Corporation
• Vericel Corporation 
• CONMED Corporation
• Collagen Solutions Plc
• Arthrex, Inc. 
• Anika Therapeutics Inc. 
• B. Braun Melsungen AG

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